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Haemostatix Ltd secures further investment in new haemostat for surgery

13th June 2011 -  Haemostatix Ltd, a biopharmaceutical company, announced that it has received an investment of £250,000 from Esperante to support development of its innovative haemostat technology. This is the third round of funding the Company has secured in the last 12 months. Haemostats are used by surgeons to manage problematic bleeding and to reduce time in the operating theatre during surgery. The products are applied in the form of sprays, gels or pads, and typically contain the enzyme thrombin, which promotes blood clotting, as the active ingredient.
Haemostatix has developed a new class of active ingredient based on a peptide that binds to another blood clotting protein, fibrinogen, instantly forming a clot.  Dr Ben Nichols, CEO of Haemostatix, commented: “There is a real need for rapid acting, ready-to-use haemostats that are safe and cost-effective, and we believe our technology can deliver these benefits to surgeons and their patients.” Haemostatix is based at Nottingham’s BioCity and was originally a spin-out from Leicester University.
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Wellcome Trust and investors back development of new surgical haemostat

5th November 2010
- Haemostatix Ltd, a biopharmaceutical company, announced today that it has received a £409,000 Translation Award from the Wellcome Trust to support development of its innovative haemostat technology. The funding coincides with an additional £459,000 investment from Spark Ventures, Catapult Venture Managers, NESTA, the Lachesis Fund and Leicester University as well as new investor, Nottingham’s Mobius Technology Ventures.

Haemostats are used by surgeons to manage problematic bleeding and to reduce time in the operating theatre during surgery. The products are applied in the form of sprays, gels or pads, and typically contain the enzyme thrombin, which promotes blood clotting, as the active ingredient.

Haemostatix has developed a new class of active ingredient based on a peptide that binds to another blood clotting protein, fibrinogen, instantly forming a clot.

Dr Ben Nichols, CEO of Haemostatix, commented: “There is a real need for rapid acting, ready-to-use haemostats that are safe and cost-effective, and we believe our technology can deliver these benefits to surgeons and their patients. We have received a lot of interest from pharmaceutical companies, and this Award and the investment, will enable us to generate more data to support the commercialisation process.”

Dr Richard Seabrook, Head of Business Development at the Wellcome Trust, said: “Bleeding is a major cause of mortality during trauma and control of bleeding during surgery is essential to the outcome of procedures. If successful, a new haemostat that bypasses the need for thrombin has the potential to make a huge impact on healthcare and the Wellcome Trust is pleased to support this project.”

Haemostatix is based at Nottingham’s BioCity and was originally a spin-out from Leicester University.

 
Haemostatix appoints new Chairman following recent investment

20th June 2008 - Haemostatix Ltd appointed Dr Robert Burns as its new non-executive Chairman. Prior to joining the Haemostatix board, Robert was CEO at Celldex Therapeutics Inc, a New Jersey based developer of cancer vaccines. Under his leadership, Celldex merged with NASDAQ listed AVANT Imunotherapeutics Inc, providing an attractive route forward for investors. Prior to this, Robert led technology licensing at the Ludwig Institute for Cancer Research in New York including transactions which resulted in the formation of Piramed (UK), Lymphatix (Finland) and Recepta (Brazil) based on Ludwig intellectual property. Robert served on the Piramed board before its acquisition by Roche and on the Lymphatix board before its acquisition by Ark Therapeutics. He has also held senior executive positions at Oxford Glycosciences (UK), British Biotech (UK) and AbT (US).

Investors back development of synthetic platelet substitute

22nd April 2008 - Haemostatix Ltd, a drug development company based at Nottingham’s BioCity and originally a spin-out from Leicester University, announced today that it has received a further £1.24 million from its existing investors (Spark Ventures, Catapult and NESTA). Haemostatix also announced the appointment of a new chief executive and a new independent non-executive director. The investment will enable Haemostatix to progress development of HaemoPlaxTM, a synthetic platelet substitute designed to replace platelets currently obtained from blood donation. Donor platelets, given by transfusion, assist in blood clotting and are currently used to treat cancer and surgical patients at risk from severe bleeding.

Dr Jonathan Gee, investment director at Spark Ventures commented that HaemoPlaxTM had shown very promising results in preliminary pre-clinical trials and that the Company was on track to take HaemoPlaxTM into clinical trials.

The new chief executive is Dr Ben Nichols. Ben brings many years of experience in the commercialization and licensing of new technologies and products in the bio-pharma industry. He has held senior commercial and general management positions in the industry. Ben’s previous post was Business Development Director for Sheffield University spin-out, Plasso Technology Ltd, where he helped the company to realize a trade sale exit.

Sarah Middleton, former CEO and co-founder of Haemostatix will become chief technical officer. Sarah, who was one of the inventors of HaemoPlaxTM, has over 30 years experience in product development in the field of haemostasis.

The new independent non-executive director, Dr. Grahaem Brown, trained as a physician and specialist in Internal Medicine. He has held senior development positions in Glaxo, Novartis, Pharmacia and UCB/Celltech, covering twenty years experience of driving global drug development from discovery through development to product launch. During this time he has played a significant part in the development of some 20 new products.

Ben Nichols commented that “There is a real clinical need for a platelet substitute as donor platelets are expensive to produce, have a very short shelf life, and need to be screened to reduce the risk of transmission of blood-borne viruses that cause Hepatitis and HIV. There is also a strong demand for new products from the pharmaceutical industry itself, with major players seeking to in-license new drugs to bolster their pipelines. In this respect the strategy at Haemostatix is clear: our role is to innovate and demonstrate proof of principle, then out-license to major pharmaceutical companies who will complete clinical development. It is a well proven, value-adding strategy,” he added.

NESTA CEO, Jonathan Kestenbaum, added: “Haemostatix is a dynamic young company driving forward an innovative product that promises to change lives. We are excited to follow our original funding and look forward to working with them as the business continues to develop.”

For further information please contact:

Jonathan Gee, SPARK Ventures:
+44 (0)20 7851 7777

Annabel O’Connor for SPARK Ventures:
+44 (0)20 7307 5339

Nicola Kane, NESTA:
+44 (0)20 7438 2608

Jonathan Earl, Catapult Venture Managers:
+44 (0)870 116 1600