PeproStat is a highly innovative topical haemostat that may be applied directly via a spray during surgery to control bleeding. The product polymerises fibrinogen into fibrin, without the need for the enzyme thrombin. This mode of action is markedly faster than thrombin-mediated fibrin formation, and improves the control of bleeding compared to marketed products; a clearly identified need in this field. The product is also easy to apply with less wash off and does not contain stabilisers such as bovine aprotinin found in current brands. Manufacturing is simple and cost of goods is highly competitive.

Two formulations of the product are in development: 

PeproStat S : this product consists of the polymerising agent alone (ie. it acts on the fibrinogen at the wound site), and will compete with thrombins.

PeproStat G : this product consists of the polymerising agent plus added fibrinogen, and will compete with fibrin sealants.

Efficacy studies on both formulations have been completed in surgical models, and the data demonstrate improved control of stronger bleeds. More...

PeproStat is based on the company’s proprietary fibrinogen-binding peptide technology. More...